Would you take Drew Brees 5th overall in your fantasy football league?

I have 2 first rounders (2 and 5) but no 4th or 5th rounder- im thinkin maybe... my first pick is Turner then deangelo(5) or mjd(5) then in the second... maybe moss and in the third reggie bush or tom brady what do u think i should do ... the other option was maybe Turner, Brees, Moss, Bush...?